Stand Up For Your Health -- Physiologists And Microbiologists Find Link Between Sitting And Poor Health:
"Physiologists analyzing obesity, heart disease, and diabetes found that the act of sitting shuts down the circulation of a fat-absorbing enzyme called lipase. They found that standing up engages muscles and promotes the distribution of lipase, which prompts the body to process fat and cholesterol, independent of the amount of time spent exercising. They also found that standing up uses blood glucose and may discourage the development of diabetes.
"The existing data, by numerous studies, are starting to show that the rates of heart disease and diabetes and obesity are doubled or sometimes even tripled in people who sit a lot," Dr. Hamilton explains. One reason, he says, is an enzyme called lipase. When it's on, fat is absorbed into the muscles, but when we sit down, lipase virtually shuts off.
"Instead, the fat will recirculate in the blood stream and go and be stored as body fat or it can clog arteries and cause diseases," Dr. Hamilton says. And it's not a small amount of fat. Plasma samples were taken from the same person after eating the same meal. When they ate sitting down, the sample was cloudy, but when they ate while standing up, it was clear.
"If you can perform a behavior while sitting or standing, I would choose standing," Dr. Hamilton says."